Delta virus hepatitis
•Delta virus coinfection/superinfection in 5-15% of HIV/HBV co-infected
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•Particularly in IVDUs, Eastern/Central/Southern Europe, sub-Saharan Africa
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•Often low levels of HBV DNA or HCV RNA
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•Often aggressive hepatic fibrosis
OR F3/F4
Lacombe et al, AIDS 2007, Boyd et al, J Viral Hepatitis 2009, Arribas et al, AIDS 200