Proposed optimal duration of HCV therapy in
HCV/HIV co-infected patients
*In patients with baseline low viral load and minimal liver fibrosis. W, week; neg, negative; pos, positive; G, genotype.
Soriano et al. AIDS 2007; 21: 1073–1089
HCV-RNA
negative
W4
W12
W24
W48
W72
G2/3
G1/4
Stop
Stop
G2/3
G1/4
24 weeks’
therapy*
48 weeks’
therapy
72 weeks’
therapy
HCV-RNA
positive
HCV-RNA
negative
HCV-RNA
positive
>2 log drop
in HCV-RNA
<2 log drop
in HCV-RNA